A SYNTHETIC LETHALITY SCREEN USING A FOCUSED SIRNA LIBRARY TO IDENTIFY SENSITIZERS TO DASATINIB THERAPY FOR THE TREATMENT OF EPITHELIAL OVARIAN CANCER.

Molecular targeted therapies have been the focus of recent clinical trials for the treatment of patients with recurrent epithelial ovarian cancer (EOC).The majority have not fared well as monotherapies for improving survival of these patients.Poor bioavailability, lack of predictive biomarkers, and the presence of multiple survival pathways can all

The traditional views about the Greeks in the Roman Empire (i.e.Rome as the new leader of Hellenism, or Greek alienation within 2006 nissan altima radio the Empire), are not enough to explain the complex process which transformed the Greeks into Romans.Firstly, a new overview is needed: when dealing with the new imperial identity, reciprocity betwe

In this paper, we analyze the radar cross section (RCS) of an integrated mast and present the optimized mast shape for RCS reduction.The RCS is simulated using commercial electromagnetic (EM) software based on the chorulon hcg shooting and bouncing rays (SBR) method and the diffraction fields at the edges are also considered.Threat frequencies, thr

Sex chromosome aneuploidies occur commonly in the general population, with an incidence of 1 in 400 newborns.However, no tests specifically targeting sex chromosomes have been carried out in prenatal diagnosis or newborn screening, resulting in late recognition of these diseases.In this study, a rapid diagnostic method for sex chromosome aneuploidi

Regina Fölster-Holst,1 Jagoda Galecka,1 Sigo Weißmantel,1 Ute Dickschat,2 aptamil allerpro Frank Rippke,3 Kerstin Bohnsack,3 Thomas Werfel,4 Katja Wichmann,4 Matthias Buchner,1 Thomas Schwarz,1 Annika Vogt,5 Jürgen Lademann,5 Martina C Meinke5 1Department of Dermatology, Venerology and Allergy, University of Kiel, 2Wörth, 3Beie